1. 3D ultrasound volume with CrystalVue™ and RealisticVue™ rendering. The volume was sectioned in a coronal plane to visualise internal structures.
2. Histological section from the Carnegie Collection. A matching imaging plane was selected to validate the structures visualised. The original specimen was sectioned in the transverse plane. The sections were imported into a digital post-processing software (Amira, ThermoFisher Scientific) and aligned. From this imaging stack, the software can recreate other imaging planes, including the coronal imaging plane as demonstrated here.
3. Cross section of a 3D embryological model based on histological sections as shown in image B, the cross section was taken in the same imaging plane as image B.

Image credit for images B and C: 3D Embryo Atlas, B.S. de Bakker et al., An interactive three-dimensional digital atlas and quantitative database of human development, Science 2016; 354

1. 3D ultrasound volume with CrystalVue™ and RealisticVue™ rendering. The volume was sectioned in a coronal plane to visualise internal structures.
2. Histological section from the Carnegie Collection. A matching imaging plane was selected to validate the structures visualised. The original specimen was sectioned in the transverse plane. The sections were imported into a digital post-processing software (Amira, ThermoFisher Scientific) and aligned. From this imaging stack, the software can recreate other imaging planes, including the coronal imaging plane as demonstrated here.
3. Cross section of a 3D embryological model based on histological sections as shown in image B, the cross section was taken in the same imaging plane as image B.

Image credit for images B and C: 3D Embryo Atlas, B.S. de Bakker et al., An interactive three-dimensional digital atlas and quantitative database of human development, Science 2016; 354

1. 3D ultrasound volume of the head and brain. The top image shows the reconstructed 2D sagittal plane selected from the volume in multiplanar mode. The bottom image shows the 3D rendered volume with CrystalVue™ and RealisticVue™ applied, sectioned in the sagittal plane.
2. The same 3D ultrasound volume with CrystalVue™ and RealisticVue™ rendering as shown in A was turned 45 degrees, so to view the back of the head and brain. The head and brain have been sectioned in a coronal plane to visualise structures located in the posterior cranial fossa. The dotted line in A indicate the sectioning plane.
3. 3D embryological model showing the same structures as those visualised in A.

Image credit for images B and C: 3D Embryo Atlas, B.S. de Bakker et al., An interactive three-dimensional digital atlas and quantitative database of human development, Science 2016; 354